PEOPLE confirms that Bush will join the medical drama in the Nov. 7 episode as Dr. Cass Beckman Sophia Bush is ready to get her scrubs back on. The actress, 42, will be joining Grey's Anatomy for the hit show's 21st season,

One Tree Hill star Sophia Bush has joined the cast of Grey's Anatomy for season 21. The Chicago PD actor is set to have a "huge recurring role" in the hit medical drama, according to Deadline. Bush will star as Seattle Presbyterian trauma surgeon Dr. Cass Beckman, whose husband David Beckman works at Grey Sloan as a cardiothoracic surgeon.